Name: Li, YingYi
|Education & Professional Experience||
2009.10- Associate Professor, Cancer Research Laboratory, Fudan University Cancer Hospital.
2008.10- Kanazawa University, Cancer Research Institute, Research Associate
2006.10-2008.9 The Japan Society for the Promotion of Science (JSPS) Postdoctoral Fellowship for Foreign Researcher
2005.4-2006.9 Venture Business Laboratory, Kanazawa University, Lecturer
2000.10-2004.12 Kanazawa University, Cancer Research Institute, Doctor of Philosophy in Medical Sciences
|Specialty||Cancer molecular bioregulation, Tumor microenvironment, Tumor metastasis|
|Research||Pancreatic cancer, Gastrointestinal cancer|
1.Ying-Yi Li, Ying-Ying Wang, Tsuyoshi Taniguchi, Takahiro Kawakami, Tomohisa Baba, Hiroyuki Ishibashi and Naofumi Mukaida. Identification of stemonamide synthetic intermediates as a novel potent anticancer drug with an apoptosis-inducing ability. International journal of cancer. 2010, (127), 474-484
2.Li Ying-Yi, Wu Yu, Tsuneyama K., Baba T., and Mukaida N. Essential Contribution of Ets-1 to constitutive Pim-3 Expression in Human Pancreatic Cancer Cells. Cancer Science, 2009, 100 (3); 396-404
3.Li Ying-Yi, Popivanova B.K., Nagai Y., Ishikura H., Fujii C., and Mukaida N., Pim-3, a proto-oncogene with serine/threonine kinase activity, is aberrantly expressed in human pancreatic cancer and phosphorylates Bad to counteract Bad-mediated apoptosis in human pancreatic cancer cell lines. Cancer Research, 2006, 66: 6041-7.
4.Li Ying-Yi, Aoki T., Mori Y., Ahmad M., Miyamori H., Takino T. and Sato H., Cleavage of Lumican by Membrane-Type Matrix Metalloproteinase-1 Abrogates This Proteoglycan-Mediated Suppression of Tumor Cell Colony Formation in Soft Agar. Cancer Research, 2004, 64: 7058-7064.
5.Wu Yu, Li Ying-Yi, Matsushima K., Baba T., and Mukaida N. CCL3-CCR5 axis regulates intratumoral accumulation of leukocytes and fibroblasts, and their angiogenic molecule expression in murine lung metastasis process. The Journal of Immunology, 2008; 181(9): 6384-93.
6.Popivanova B.K., Li Ying-Yi, Zheng, H., Fujii C., Tsuneyama K., and Mukaida N., A proto-oncogene, Pim-3 with serine/threonine kinase activity, is aberrantly expressed in human colon cancer cells and can prevent Bad-mediated apoptosis. Cancer Science, 2007; 98: 321–328